Meticore is an FDA-approved new supplement on the market which includes 250mg of ingredients like Fucoxanthin, Citrus Bioflavanoids (citrus aurantium fruit), Moringa (moringa oleifera), Ginger Rhizome (Zingiber officinale), African Mango Seed (Irvingia gabonensis), Turmeric Rhizome (Curcuma longa). Works for men and women.

Add to that added 10mcg of Vitamin B12 (as Cyanocobalamin) and 35mcg of Chromium (as Chromium Picolinate). The 10mcg Cyanocobalamin is not much at all, so even if you have MTHFR mutation, as 25% of global population have it, this amount should not really affect your regular daily life.

The Meticore works as weight loss supplement by boosting metabolic function and hormonal optimization. Let’s talk in short about a couple of ingredients and why they work for weight loss.

Here is information about Fucoxanthin from official government studies (foreign government).

Fucoxanthin, an allenic carotenoid, can be isolated from edible brown seaweeds. Recent studies have reported that fucoxanthin has many physiological functions and biological properties, such as antiobesity, antitumor, antidiabetes, antioxidant, anti-inflammatory, and hepatoprotective activities, as well as cardiovascular and cerebrovascular protective effects. 

Therefore, fucoxanthin can be used as both medicinal and nutritional ingredient to prevent and treat chronic diseases.Fucoxanthin: A Promising Medicinal and Nutritional Ingredient

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461761/

So, here we have a natural ingredient derived from seaweed. And seaweed is well known for many of nutritional and metabolic properties. In Japan, seaweed and se products make up a significant portion of the diet, and results are evident – very few obese people in Japan.

Here is more from that study, with evidence why this ingredient works: 

 The study by Hashimoto et al. [] showed that the bioavailability of fucoxanthinol was higher in human subjects than in mice. They also found that the metabolism of fucoxanthin differed between human subjects and mice. Fucoxanthinol is considered to be the primary active metabolite in human. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4461761/

And even more:

Fucoxanthin is a safe pharmaceutical ingredient. Clinical research showed that taking fucoxanthin was thought to speed up metabolism, but the metabolic boost did not stimulate the central nervous system

Consequently, finding efficient strategies to prevent obesity is crucial. Researchers found that fucoxanthin supplementation could play a beneficial role in antiobesity through various pathways (Figure 3).

Here is information from another medical scientific source: “Accumulating data suggest that food supplementation with seaweeds which traditionally are an important part of food culture in South-East Asian countries might lead to essential health benefits. 

In this short review, we summarize findings from experimental studies on the effects of fucoxanthin (a carotenoid derived from brown seaweeds) on lipid metabolism, adiposity, and related conditions and discuss the possible underlying mechanisms.” https://www.nmcd-journal.com/article/S0939-4753(15)00140-4/abstract

The anti-obesity effects of fucoxanthin are apparently mediated by the hormones leptin and adiponectin through their common target AMK-activated protein kinase, resulting in downregulation of lipogenic enzymes and upregulation of lipolytic enzymes. Fucoxanthin also suppresses adipocyte differentiation and induces the expression of uncoupling proteins in visceral adipose tissue.


Conclusion

The results of experimental studies suggest that consumption of fucoxanthin and its derivatives as nutritional supplements is a promising option for prevention and treatment of obesity and a wide variety of related pathologies, including metabolic syndrome, type 2 diabetes, and heart disease. Yet, clinical trials are warranted to assess a therapeutic value of fucoxanthin.” https://www.nmcd-journal.com/article/S0939-4753(15)00140-4/abstract

 


 

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